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Case Report

Mixed epithelial and stromal tumor in a young male case with hydronephrotic nonfunctional kidney: Comparison with literature findings


1  Bezmialem Vakıf University, Faculty of Medicine, Department of Pathology, Istanbul, Turkey
2 Bezmialem Vakıf University, Faculty of Medicine, Department of Urology, Istanbul, Turkey

ABSTRACT

The mixed epithelial and stromal tumor (MEST) family is comprised of adult cystic nephroma with a dominant cystic component and MEST with a dominant solid component. MEST is the rarely observed benign, biphasic tumor of the kidney with a mixed epithelial and stromal component. In the examinations of a 24-year-old male patient who presented with abdominal pain, grade-4 hydronephrosis was detected. In the microscopic examination of his nephrectomy specimen, there were tubular structures with cu-boidal epithelium in different diameters within the ovarian stroma. The patient was diagnosed with MEST via morphological and immunohistochem-ical findings. We aimed at comparing the clinical and histopathological characteristics of our case, which we diagnosed with MEST, which is encoun-tered in limited numbers in young men and has never been reported together with a nonfunction-al kidney before, to the literature data. 

Keywords: Mixed epithelial and stromal tu-mor, nonfunctional kidney, male.


ABSTRACT

The mixed epithelial and stromal tumor (MEST) family is comprised of adult cystic nephroma with a dominant cystic component and MEST with a dominant solid component. MEST is the rarely observed benign, biphasic tumor of the kidney with a mixed epithelial and stromal component. In the examinations of a 24-year-old male patient who presented with abdominal pain, grade-4 hydronephrosis was detected. In the microscopic examination of his nephrectomy specimen, there were tubular structures with cu-boidal epithelium in different diameters within the ovarian stroma. The patient was diagnosed with MEST via morphological and immunohistochem-ical findings. We aimed at comparing the clinical and histopathological characteristics of our case, which we diagnosed with MEST, which is encoun-tered in limited numbers in young men and has never been reported together with a nonfunction-al kidney before, to the literature data. 

Keywords: Mixed epithelial and stromal tu-mor, nonfunctional kidney, male.

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